This is a reprint of the MDPI IJERPH Special Issue entitled "COVID-19 and Environment: Impacts of a Global Pandemic". The reprint consists of 17 papers with different topics related to the COVID-19 pandemic and environmental impacts using data from different countries all over the globe.

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Lipid-based nanosystems, including solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs), cationic lipid nanoparticles, nanoemulsions, and liposomes, have been extensively studied to improve drug delivery through different administration routes. The main advantages of these systems are their ability to protect, transport, and control the release of lipophilic and hydrophilic molecules (either small-molecular-weight molecules or macromolecules); the use of generally recognized as safe (GRAS) excipients that minimize the toxicity of the formulations; and the possibility to modulate pharmacokinetics and enable the site-specific delivery of encapsulated payloads. In addition, the versatility of lipid-based nanosystems has further been demonstrated for the delivery of vaccines, the protection of active cosmetic ingredients, and the improvement of moisturizing properties of cosmetic formulations.Lipid-based nanosystems are well established and there are already different commercially approved formulations for various human disorders. This success has paved the way for the diversification of the pipeline of development, to address unmet medical needs for several indications, such as cancer, neurological disorders, and autoimmune, genetic, and infectious diseases.This Special Issue aims to update readers on the latest research on lipid-based nanosystems, both at the preclinical and clinical levels. A series of 15 articles (six reviews and nine studies) is presented, with authors from 12 different countries, showing the globality of the investigations that are being carried out in this area.

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Our Special Issue is aimed at examining the continuous evolution within our discipline and the vastness of it. This Issue is a collection and presentation of data on the latest developments in the field of dermatology and is intended to be a continuation of articles previously published by the Guest Editors. Dermatology is a continuously evolving specialty and touches on every part of the field of medicine. This Special Issue of Diagnostics entitled “Diagnosis and Management of Skin Diseases, Related Disorders and Their Comorbidities” aims to collect and present data about the most recent developments in the field. Medical history and clinical examination, followed by non-invasive imaging or blood tests or the exploration of skin structures and their pathological changes, allow pathologists to better understand, detect, or define diseases of the skin. We clinicians and researchers are constantly viewing cutaneous signs and symptoms as a window into the systemic state of the human body. Many diseases thought to be localized to the skin are now considered part of a systemic involvement. Each of our patients is unique, with their own comorbidities and anatomic or physiologic particularities. There are also individual aspects regarding the appearance, evolution, and prognosis of cutaneous skin diseases, as well as their response to various treatments.

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

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The book entitled Medicinal Plants and Natural Product Research describes various aspects of ethnopharmacological uses of medicinal plants; extraction, isolation, and identification of bioactive compounds from medicinal plants; various aspects of biological activity such as antioxidant, antimicrobial, anticancer, immunomodulatory activity, etc., as well as characterization of plant secondary metabolites as active substances from medicinal plants.

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This Special Issue explores the range of clinical manifestations and epidemiology of both skin NTDs and common skin disease in endemic regions, the use of common diagnostic and management pathways, the different technologies that play a role in diagnosis and training, the role of patient involvement at a community level, as well as the assessment of the results of different initiatives in the field.

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